Recent articles & letters
Before entering into any type of chemo therapy it is useful to understand that the norm in treating most cancers is to assess through biopsy using microscopic, morphologic identification and staining. The treatment is then based upon statistical outcome studies of various tumor types. Chemo therapeutic and, more recently, some targeted monoclonal or tyrosine kinase inhibiting agents are selected. The problem with this approach is twofold; first, Nature doesn’t divide cancers into neat organ selective types but rather much more complex onco genetic sequences occuring in tissue types and secondly, if one uses the wrong agent (s) then the cancer often becomes more aggressive. Onco genetic identification is a way of identifying the specific activating and enabling genes of the cancer. Since the tumor is not the cancer but rather an expression of the cancer, circulating seeds known as circulating tumor cells present a unique cell line for more homogenous tumor gene analysis. Since all persons with metastasizing type cancers will almost always have these cells circulating in their blood, analyzing these cells through a blood test is a unique means of objectively determining which treatments will more likely be effective in any given individual. One big problem with statistical, double blind studies of cancer populations is that individualized assessment and treatment is neither targeted or desired. Until clinical medicine catches up with the biology, genetics and physiology of cancer science, optimal therapeutic outcomes will continue to be the exception rather then the norm in treating most cancers. In other words, people will continue to die in much greater numbers because the so-called “Standard of Care” is to, 1.) expect the patient to die within one to five years or less, 2.) declare war on the cancer and then nail the cancer and patient with maximum doses of cytotoxic chemicals while ignoring all alternative approaches until the first and second line treatment protocols have been exhausted, the patient is nearly dead and there will be no medical-legal problem introducing innovations. Knowing this it is easy to see why stepping outside the box may be a medical necessity in surviving both the cancer and its prescribed treatment.
I really appreciate your sharing your knowledge and the fact that you do not
push me hard, but rather put the information out there for me to consider.
But I am a skeptical and relentlessly logical being.
I’ve been researching this online, and, other than the New Mexico
study–which was for pancreatic cancer–find very little about its use in
cancer treatment. From what I’m finding, LDN is used mainly for MS, Crohn’s
disease, and fibromyalgia, while ALA is used mainly on liver disease and
And from what I’m seeing, there don’t seem to be many studies demonstrating
the efficacy of either in treating any of the conditions they’re used for.
Re Y., how do you know whether her lower numbers relate to the ALA/LDN
or the new chemo?
Again, I’m sorry to be so skeptical, but I can’t help it.
P.S. I’m scheduled to begin the Gemcitobine on Monday.
P.P.S. My spirits have been so much better since the visit to Mendocino,
though here again, do I attribute that to the Mood Sync or having gotten
away? (I’m leaning toward the latter since it seems unlikely that the Mood
Sync would act that quickly.)
True but consider this: Chemo therapeutic protocol results and studies
are not based upon your particular cancer genetics either. Therefore,
it’s all just guess work unless you do oncogenetic profiling and
pharmacogenetic testing to individualize the treatment. This is not to
mention the fact that if they “f up” on the choice of chemo it will
very probably aggravate the cancer and cause it to become more
aggressive while at the same time weakening your bone marrow and native
immune defense which is critical to long term survival. The nutrient
based therapies will not do this whether effective or not and the
intention behind their use is synergism with other therapies. Also,
it is well known that single agent therapies are less effective long
term because they are more likely to allow the cancer genetics to match
and adapt then mutate and become stronger. Synergism of several therapies,
including targeted tyrosine kinase inhibitors such as Urbitux as well as
nutrient based oxidative therapies allow a broader stance and tack down
more oncogenes making adaptation and escape less likely. This is a proven
clinical and experimental fact. So let’s look at the real science and
biology of cancer and understand it instead of falling in line with the
normal, and might I add corrupt, medical machine pumping bodies through
a one size fits all keyhole in a door leading to biological disaster while
the other door of biological reality stands wide open next to it. This is
not to say your oncologist is other then sincere, it’s just that the
science behind the decision making process in “standard of care” oncology
is inherently weak and inaccurate. The corruption is so pervasive that it
is seamless as well as seemless.
I’m glad you’re feeling better R. I’d say the Mendo experience is a
seed of hope, the capsules will nourish this, and my hope is that you will
I love you bro,
To: Dan Dunphy
Subject: Re: ALA/LDN
I’m leaning toward doing this and will decide this week.
A couple of questions:
* Where, exactly, is your office and how easy is it to get there from Muni?
(I assume I’d take BART to the city then switch to Muni; just wondering how
far I’d have to walk.)
* What would you charge me?
* Can you point me to a web page that offers a concise explanation of
Our clinic is right on West Portal so you can take BART to any downtown
exit and switch to the K or M. Get off at West Portal and 14th
The corner where there’s a B of A. Walk down the street and cross
over to the south side of West Portal, 345 West Portal. We’re on
the second floor. The cost of each iv infusion is around $180.
You have to understand that double blind studies for the FDA cost $10,000,000
average and must be paid for by the company wanting to market a product.
Therefore, there are hardly any studies performed on natural therapies since
you can’t take out a patent on them and who’s going to spend $10,000,000 on
something they can’t market exclusively? No one. So, except for the NIH
alternative medicine department, with it’s very limited budget, there’s hardly
any classic studies done on many natural oxidative, anti angiogenic or apoptosis
inducing therapies for cancer. Add to this the fact that in California it is a Felony
for any practitioner to offer any therapy other then Chemo,radiation or surgery
for cancer and you can begin to understand why you can’t find any “literature”
on LDN or ALA, let alone an oncologist willing to authorize it’s use for patients.
There is one oncologist I work with in SF, Dr. G.S., MD, who is Y’s oncologist
who has unofficially encouraged her to do nutrient therapies along with her chemo protocol.
You could also write or call my patient Y. I will ask her for permission first.
Considering your response to this chemo agent the first time, it is reasonable,
if wearing scientific blinders and just using statistical, best guess approach,
to offer you a therapy which has been successful for you in the past. I would
recommend the high dose vitamin C, quercitin oxidative therapy to you to support
your bone marrow and immune function on off weeks during your treatment. If you
would like to try the ALA, LDN I will set that up for you as well.
I also get referrals from UC SF Med Center oncologists for high dose vitamin c
therapy for their patients. It’s all an underground arena. Moreover, there’s the
issue, which I was writing to you about the other day, namely individualizing cancer
therapy according to individual oncogenetic profiling and pharmacogenetic testing.
This is clearly “the future” as oncologists are fond of saying. Unfortunately, the
future is not soon enough for someone who’s future depends upon accurate treatment.
Eventhough the science is here, clinical medicine is dragging its feet, hands, scalpels
and wallets into that “future” whose day has already come but which is being largely
ignored. I’m really not a big advocate of LDN or ALA therapy per se unless there is
pretesting to validate it’s use from oncogenetic standpoint. I am a big advocate of
high dose vitamin C, quercitin ivs since 99% of the 60+ RGCC lab tests I’ve performed
on patients over the last 6 years show positive anti oncogenetic effects of these nutrients.
They also seem to diminish side effects and enhance outcomes plus they can be continued
after chemo therapy to effectively block the tumorgenic rebound often experienced
several weeks to months after chemo has been stopped.
Here are a few links:
Please stay in touch and let me know how I can help you.
Posted on November 8, 2010 by Daniel
Dearest Dr. Dunphy,
I thought you would like to see what A. wrote me about you. I’m very happy that he
finally listened to me – I’ve been telling him about you for a long time (right after
the first visit for my sister, in March (?) 2009). Ever since I met you I can’t stop
talking and telling people that if they are serious about their health, and ultimately,
their lives, they should do everything in their power to go to you.
Today I know that if I had met you before my beloved brother, J., innocent, kind, super
simple, humble, young man (much younger than me), died in 2008, HE WOULD BE ALIVE TODAY.
I tried so hard to find the “RIGHT” professional to take him to. I asked dozens of
times, dozens of people, at the R. store. I spent hours there every Saturday hoping to
get a name, a lead, to that man. I begged. I pleaded. I got other names; we
took him, we spent all the $ we had (that’s is one of the reasons we are totally broken
this time), only to find out that those people, so called MDs, etc.. were nothing but
disguised crooks. The irony is that when my sister got sick on December 20, 2008 we
were lost, full of disbelieve, afraid, and suspicious. We got new names, and went to
new “crooks”. Because of our recent experience we knew we were on the wrong road.
Until that blessed day at the R. store when one of the workers told me about A. and
how much she respected, trusted and adored you. I got her phone and called her for a
whole week till one day she answered. She told me that you were not the MD but the
physician associate. “I don’t care what he is, all I want is a human being knowledgeable,
honest and passionate about what he does, specially if that has to do with some ones’s
life.” The rest is history. I asked for a sandwich and, God in His wisdom and kindness,
gave us a banquet. How lucky bottom of my heart. Because of what we had to go though to
find you, I’m always so anxious to talk about you and to tell people to go to you. I
go out of my way to reach people, to let them know what you can do for them, etc..
because I know how frustrating it is “finding” THE “solid guy”, like A. calls you.
Sometimes I get mad – they get the information for free, and don’t appreciate it.
Probably A. told you about his friend S. – he is very, very ill. I insisted for him
to go to you over 2 months ago. He got worse, and worse, and now, A. tells me that
he has an appointment for next week. I wish him the best. May God look upon him and
you to guide him the right way, if this is not yet his time “to go”,
I love you. Sorry for taking so much of your time with all my stories.
Take care. Regards for the family.
Thank you for your elegantly written letter. I so much appreciate what
you have written, it makes long hours of effort all worth while. My patients are my
best teachers always. When we listen and observe intently , what is before us becomes
deeper then what is apparent. The soul of the person emerges from behind all the
appearances. Knowing and appreciating that depth allows one to see “the therapeutic
handle” to hold and turn so that the person gains confidence in their own body’s
ability to heal. There is often much more work to be done after this healing moment
but one proceeds in confidence, hope and inner calm, floating atop rather then drowned
by adversity. My favorite Chinese aphorism remains, “Flowers bloom in the midst of
adversity.” It’s true.
Thank you with Warm Regards to you and your family too,
PS Thanks for your kind referral. I really enjoyed meeting A.